Effect of treadmill exercise on PI3K/AKT/mTOR, autophagy, and Tau hyperphosphorylation in the cerebral cortex of NSE/htau23 transgenic mice

PURPOSE: Neurofibrillary tangles, one of pathological features of Alzheimer’s disease, are produced by the hyperphosphorylation and aggregation of tau protein. This study aimed to investigate the effects of treadmill exercise on PI3K/AKT/mTOR signal transmission, autophagy, and cognitive ability tha...

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Detalles Bibliográficos
Autores principales: Kang, Eun-Bum, Cho, Joon-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Exercise Nutrition 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624121/
https://www.ncbi.nlm.nih.gov/pubmed/26527331
http://dx.doi.org/10.5717/jenb.2015.15090806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624121/
https://www.ncbi.nlm.nih.gov/pubmed/26527331
http://dx.doi.org/10.5717/jenb.2015.15090806

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