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Evolution of the highly networked deubiquitinating enzymes USP4, USP15, and USP11

BACKGROUND: USP4, USP15 and USP11 are paralogous deubiquitinating enzymes as evidenced by structural organization and sequence similarity. Based on known interactions and substrates it would appear that they have partially redundant roles in pathways vital to cell proliferation, development and inna...

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Detalles Bibliográficos
Autores principales: Vlasschaert, Caitlyn, Xia, Xuhua, Coulombe, Josée, Gray, Douglas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624187/
https://www.ncbi.nlm.nih.gov/pubmed/26503449
http://dx.doi.org/10.1186/s12862-015-0511-1