Handling Permutation in Sequence Comparison: Genome-Wide Enhancer Prediction in Vertebrates by a Novel Non-Linear Alignment Scoring Principle

Enhancers have been described to evolve by permutation without changing function. This has posed the problem of how to predict enhancer elements that are hidden from alignment-based approaches due to the loss of co-linearity. Alignment-free algorithms have been proposed as one possible solution. How...

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Detalles Bibliográficos
Autores principales: Dolle, Dirk, Mateo, Juan L., Eichenlaub, Michael P., Sinn, Rebecca, Reinhardt, Robert, Höckendorf, Burkhard, Inoue, Daigo, Centanin, Lazaro, Ettwiller, Laurence, Wittbrodt, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624239/
https://www.ncbi.nlm.nih.gov/pubmed/26505748
http://dx.doi.org/10.1371/journal.pone.0141487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624239/
https://www.ncbi.nlm.nih.gov/pubmed/26505748
http://dx.doi.org/10.1371/journal.pone.0141487

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