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Redox Regulation of Pro-IL-1β Processing May Contribute to the Increased Severity of Serum-Induced Arthritis in NOX2-Deficient Mice

Aims: To elucidate the role of reactive oxygen species (ROS) in arthritis and to identify targets of arthritis treatment in conditions with different levels of oxidant stress. Results: Through establishing an arthritis model by injecting arthritogenic serum into wild-type and NADPH oxidase 2 (NOX2)-...

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Detalles Bibliográficos
Autores principales: Huang, Ya-Fang, Lo, Pei-Chi, Yen, Chia-Liang, Nigrovic, Peter Andrija, Chao, Wen-Chen, Wang, Wei-Zhi, Hsu, George Chengkang, Tsai, Yau-Sheng, Shieh, Chi-Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624247/
https://www.ncbi.nlm.nih.gov/pubmed/25867281
http://dx.doi.org/10.1089/ars.2014.6136