Podocyte-specific deletion of NDST1, a key enzyme in the sulfation of heparan sulfate glycosaminoglycans, leads to abnormalities in podocyte organization in vivo

Heparan sulfate proteoglycans have been shown to modulate podocyte adhesion to- and pedicel organization on- the glomerular basement membrane. Recent studies showed that foot process effacement developed in a mutant mouse model whose podocytes were unable to assemble heparan sulfate glycosaminoglyca...

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Detalles Bibliográficos
Autores principales: Sugar, Terrel, Wassenhove-McCarthy, Deborah J, Esko, Jeffrey D, van Kuppevelt, Toin H, Holzman, Lawrence, McCarthy, Kevin J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624314/
https://www.ncbi.nlm.nih.gov/pubmed/23924956
http://dx.doi.org/10.1038/ki.2013.281

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624314/
https://www.ncbi.nlm.nih.gov/pubmed/23924956
http://dx.doi.org/10.1038/ki.2013.281

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