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5-HT1A Receptors on Mature Dentate Gyrus Granule Cells are Critical for the Antidepressant Response

Selective serotonin reuptake inhibitors (SSRIs) are widely used antidepressants, but the mechanisms by which they influence behavior are only partially resolved. Adult hippocampal neurogenesis is necessary for some of the responses to SSRIs, but it is unknown whether the mature dentate gyrus granule...

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Detalles Bibliográficos
Autores principales: Samuels, Benjamin Adam, Anacker, Christoph, Hu, Alice, Levinstein, Marjorie R., Pickenhagen, Anouchka, Tsetsenis, Theodore, Madroñal, Noelia, Donaldson, Zoe R., Drew, Liam John, Dranovsky, Alex, Gross, Cornelius T., Tanaka, Kenji F., Hen, René
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624493/
https://www.ncbi.nlm.nih.gov/pubmed/26389840
http://dx.doi.org/10.1038/nn.4116