Phenotypic Tfh development promoted by CXCR5-controlled re-localization and IL-6 from radiation-resistant cells

How follicular T-helper (Tfh) cells develop is incompletely understood. We find that, upon antigen exposure in vivo, both naïve and antigen-experienced T cells sequentially upregulate CXCR5 and Bcl6 within the first 24 h, relocate to the T-B border, and give rise to phenotypic Bcl6(+)CXCR5(+) Tfh ce...

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Detalles Bibliográficos
Autores principales: Chen, Xin, Ma, Weiwei, Zhang, Tingxin, Wu, Longyan, Qi, Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624673/
https://www.ncbi.nlm.nih.gov/pubmed/26404031
http://dx.doi.org/10.1007/s13238-015-0210-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624673/
https://www.ncbi.nlm.nih.gov/pubmed/26404031
http://dx.doi.org/10.1007/s13238-015-0210-0

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