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Phenotypic Tfh development promoted by CXCR5-controlled re-localization and IL-6 from radiation-resistant cells
How follicular T-helper (Tfh) cells develop is incompletely understood. We find that, upon antigen exposure in vivo, both naïve and antigen-experienced T cells sequentially upregulate CXCR5 and Bcl6 within the first 24 h, relocate to the T-B border, and give rise to phenotypic Bcl6(+)CXCR5(+) Tfh ce...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Higher Education Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624673/ https://www.ncbi.nlm.nih.gov/pubmed/26404031 http://dx.doi.org/10.1007/s13238-015-0210-0 |