Cargando…

Apaf1 inhibition promotes cell recovery from apoptosis

The protein apoptotic protease activating factor 1 (Apaf1) is the central component of the apoptosome, a multiprotein complex that activates procaspase-9 after cytochrome c release from the mitochondria in the intrinsic pathway of apoptosis. We have developed a vital method that allows fluorescence-...

Descripción completa

Detalles Bibliográficos
Autores principales: Gortat, Anna, Sancho, Mónica, Mondragón, Laura, Messeguer, Àngel, Pérez-Payá, Enrique, Orzáez, Mar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624680/
https://www.ncbi.nlm.nih.gov/pubmed/26361785
http://dx.doi.org/10.1007/s13238-015-0200-2