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Apaf1 inhibition promotes cell recovery from apoptosis
The protein apoptotic protease activating factor 1 (Apaf1) is the central component of the apoptosome, a multiprotein complex that activates procaspase-9 after cytochrome c release from the mitochondria in the intrinsic pathway of apoptosis. We have developed a vital method that allows fluorescence-...
Autores principales: | Gortat, Anna, Sancho, Mónica, Mondragón, Laura, Messeguer, Àngel, Pérez-Payá, Enrique, Orzáez, Mar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Higher Education Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624680/ https://www.ncbi.nlm.nih.gov/pubmed/26361785 http://dx.doi.org/10.1007/s13238-015-0200-2 |
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