Dysfunctional Presynaptic M(2) Receptors in the Presence of Chronically High Acetylcholine Levels: Data from the PRiMA Knockout Mouse

The muscarinic M(2) receptor (M2R) acts as a negative feedback regulator in central cholinergic systems. Activation of the M(2) receptor limits acetylcholine (ACh) release, especially when ACh levels are increased because acetylcholinesterase (AChE) activity is acutely inhibited. Chronically high AC...

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Detalles Bibliográficos
Autores principales: Mohr, Franziska, Krejci, Eric, Zimmermann, Martina, Klein, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624712/
https://www.ncbi.nlm.nih.gov/pubmed/26506622
http://dx.doi.org/10.1371/journal.pone.0141136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624712/
https://www.ncbi.nlm.nih.gov/pubmed/26506622
http://dx.doi.org/10.1371/journal.pone.0141136

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