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Predicting the Effect of Mutations on Protein-Protein Binding Interactions through Structure-Based Interface Profiles
The formation of protein-protein complexes is essential for proteins to perform their physiological functions in the cell. Mutations that prevent the proper formation of the correct complexes can have serious consequences for the associated cellular processes. Since experimental determination of pro...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624718/ https://www.ncbi.nlm.nih.gov/pubmed/26506533 http://dx.doi.org/10.1371/journal.pcbi.1004494 |