Expression of a Chimeric Antigen Receptor in Multiple Leukocyte Lineages in Transgenic Mice

Genetically modified CD8(+) T lymphocytes have shown significant anti-tumor effects in the adoptive immunotherapy of cancer, with recent studies highlighting a potential role for a combination of other immune subsets to enhance these results. However, limitations in present genetic modification tech...

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Detalles Bibliográficos
Autores principales: Yong, Carmen S. M., Westwood, Jennifer A., Schröder, Jan, Papenfuss, Anthony T., von Scheidt, Bianca, Moeller, Maria, Devaud, Christel, Darcy, Phillip K., Kershaw, Michael H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624721/
https://www.ncbi.nlm.nih.gov/pubmed/26505904
http://dx.doi.org/10.1371/journal.pone.0140543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624721/
https://www.ncbi.nlm.nih.gov/pubmed/26505904
http://dx.doi.org/10.1371/journal.pone.0140543

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