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Apelin-13 protects the heart against ischemia-reperfusion injury through the RISK-GSK-3β-mPTP pathway

INTRODUCTION: Apelin plays an important role in the protection against myocardial ischemia-reperfusion (I/R) injury, while the mechanism still remains unclear. In the current study, we aimed to evaluate the protective effect of apelin-13, and the main mechanism. MATERIAL AND METHODS: The in vivo I/R...

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Detalles Bibliográficos
Autores principales: Yang, Shuansuo, Li, Hui, Tang, Lei, Ge, Guanghao, Ma, Jiangwei, Qiao, Zengyong, Liu, Huajin, Fang, Weiyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624751/
https://www.ncbi.nlm.nih.gov/pubmed/26528352
http://dx.doi.org/10.5114/aoms.2015.54863