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FK506-binding protein 5 inhibits proliferation and stimulates apoptosis of glioma cells

INTRODUCTION: FK506-binding protein 5 (FKBP5) is reported to act as a scaffolding protein for Akt to promote the dephosphorylation of AKT Ser473 and suppress pancreatic cancer growth. However, other studies have shown that FKBP5 promotes tumor growth and chemoresistance through regulating NF-κB sign...

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Detalles Bibliográficos
Autores principales: Yang, Hui, Zhang, Qing-Xiu, Pei, Dong-Sheng, Xu, Feng, Li, Yong, Yu, Ru-Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624752/
https://www.ncbi.nlm.nih.gov/pubmed/26528353
http://dx.doi.org/10.5114/aoms.2015.54864