Deficiency of Calcium-Independent Phospholipase A2 Beta Induces Brain Iron Accumulation through Upregulation of Divalent Metal Transporter 1

Mutations in PLA2G6 have been proposed to be the cause of neurodegeneration with brain iron accumulation type 2. The present study aimed to clarify the mechanism underlying brain iron accumulation during the deficiency of calcium-independent phospholipase A2 beta (iPLA(2)β), which is encoded by the...

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Detalles Bibliográficos
Autores principales: Beck, Goichi, Shinzawa, Koei, Hayakawa, Hideki, Baba, Kousuke, Yasuda, Toru, Sumi-Akamaru, Hisae, Tsujimoto, Yoshihide, Mochizuki, Hideki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624760/
https://www.ncbi.nlm.nih.gov/pubmed/26506412
http://dx.doi.org/10.1371/journal.pone.0141629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624760/
https://www.ncbi.nlm.nih.gov/pubmed/26506412
http://dx.doi.org/10.1371/journal.pone.0141629

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