Cargando…

Peptides Interfering 3A Protein Dimerization Decrease FMDV Multiplication

Nonstructural protein 3A is involved in relevant functions in foot-and-mouth disease virus (FMDV) replication. FMDV 3A can form homodimers and preservation of the two hydrophobic α-helices (α1 and α2) that stabilize the dimer interface is essential for virus replication. In this work, small peptides...

Descripción completa

Detalles Bibliográficos
Autores principales: González-Magaldi, Mónica, Vázquez-Calvo, Ángela, de la Torre, Beatriz G., Valle, Javier, Andreu, David, Sobrino, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624780/
https://www.ncbi.nlm.nih.gov/pubmed/26505190
http://dx.doi.org/10.1371/journal.pone.0141415