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Residues 39-56 of Stem Cell Factor Protein Sequence Are Capable of Stimulating the Expansion of Cord Blood CD34(+) Cells

BACKGROUND: Stem cell factor (SCF) can stimulate hematopoietic stem cell (HSC) expansion; however, the specific structural region(s) of SCF protein that are critical for this function are still unknown. A novel monoclonal antibody (named 23C8) against recombinant human SCF (rhSCF) was previously fou...

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Detalles Bibliográficos
Autores principales: Shen, Bin, Jiang, Wenhong, Fan, Jie, Dai, Wei, Ding, Xinxin, Jiang, Yongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624785/
https://www.ncbi.nlm.nih.gov/pubmed/26505626
http://dx.doi.org/10.1371/journal.pone.0141485