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IRBIT Interacts with the Catalytic Core of Phosphatidylinositol Phosphate Kinase Type Iα and IIα through Conserved Catalytic Aspartate Residues

Phosphatidylinositol phosphate kinases (PIPKs) are lipid kinases that generate phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)), a critical lipid signaling molecule that regulates diverse cellular functions, including the activities of membrane channels and transporters. IRBIT (IP(3) R-binding pr...

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Detalles Bibliográficos
Autores principales: Ando, Hideaki, Hirose, Matsumi, Gainche, Laura, Kawaai, Katsuhiro, Bonneau, Benjamin, Ijuin, Takeshi, Itoh, Toshiki, Takenawa, Tadaomi, Mikoshiba, Katsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624786/
https://www.ncbi.nlm.nih.gov/pubmed/26509711
http://dx.doi.org/10.1371/journal.pone.0141569