Ticagrelor Does Not Inhibit Adenosine Transport at Relevant Concentrations: A Randomized Cross-Over Study in Healthy Subjects In Vivo

BACKGROUND AND PURPOSE: In patients with myocardial infarction, ticagrelor reduces cardiovascular and sepsis-related mortality, and can cause dyspnea. It is suggested that this is caused by adenosine receptor stimulation, because in preclinical studies, ticagrelor blocks the nucleoside transporter a...

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Detalles Bibliográficos
Autores principales: van den Berg, T. N. A., El Messaoudi, S., Rongen, G. A., van den Broek, P. H. H., Bilos, A., Donders, A. R. T., Gomes, M. E., Riksen, N. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624811/
https://www.ncbi.nlm.nih.gov/pubmed/26509673
http://dx.doi.org/10.1371/journal.pone.0137560

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624811/
https://www.ncbi.nlm.nih.gov/pubmed/26509673
http://dx.doi.org/10.1371/journal.pone.0137560

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