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Multiplex Identification of Antigen-Specific T Cell Receptors Using a Combination of Immune Assays and Immune Receptor Sequencing

Monitoring antigen-specific T cells is critical for the study of immune responses and development of biomarkers and immunotherapeutics. We developed a novel multiplex assay that combines conventional immune monitoring techniques and immune receptor repertoire sequencing to enable identification of T...

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Detalles Bibliográficos
Autores principales: Klinger, Mark, Pepin, Francois, Wilkins, Jen, Asbury, Thomas, Wittkop, Tobias, Zheng, Jianbiao, Moorhead, Martin, Faham, Malek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624875/
https://www.ncbi.nlm.nih.gov/pubmed/26509579
http://dx.doi.org/10.1371/journal.pone.0141561