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Multiplex Identification of Antigen-Specific T Cell Receptors Using a Combination of Immune Assays and Immune Receptor Sequencing
Monitoring antigen-specific T cells is critical for the study of immune responses and development of biomarkers and immunotherapeutics. We developed a novel multiplex assay that combines conventional immune monitoring techniques and immune receptor repertoire sequencing to enable identification of T...
Autores principales: | Klinger, Mark, Pepin, Francois, Wilkins, Jen, Asbury, Thomas, Wittkop, Tobias, Zheng, Jianbiao, Moorhead, Martin, Faham, Malek |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624875/ https://www.ncbi.nlm.nih.gov/pubmed/26509579 http://dx.doi.org/10.1371/journal.pone.0141561 |
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