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Interleukin17A Promotes Postoperative Cognitive Dysfunction by Triggering β-Amyloid Accumulation via the Transforming Growth Factor-β (TGFβ)/Smad Signaling Pathway

Although postoperative cognitive dysfunction (POCD) is relatively common in elderly patients who have undergone major surgery, the mechanisms underlying this postoperative complication are unclear. Previously, we have investigated the role of cytokine-mediated hippocampal inflammation in the develop...

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Detalles Bibliográficos
Autores principales: Tian, Ayong, Ma, Hong, Zhang, Rongwei, Tan, Wenfei, Wang, Xiaolong, Wu, Binyang, Wang, Jun, Wan, Chengfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624903/
https://www.ncbi.nlm.nih.gov/pubmed/26509545
http://dx.doi.org/10.1371/journal.pone.0141596