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Silencing of X-Linked MicroRNAs by Meiotic Sex Chromosome Inactivation
During the pachytene stage of meiosis in male mammals, the X and Y chromosomes are transcriptionally silenced by Meiotic Sex Chromosome Inactivation (MSCI). MSCI is conserved in therian mammals and is essential for normal male fertility. Transcriptomics approaches have demonstrated that in mice, mos...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624941/ https://www.ncbi.nlm.nih.gov/pubmed/26509798 http://dx.doi.org/10.1371/journal.pgen.1005461 |