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Silencing of X-Linked MicroRNAs by Meiotic Sex Chromosome Inactivation

During the pachytene stage of meiosis in male mammals, the X and Y chromosomes are transcriptionally silenced by Meiotic Sex Chromosome Inactivation (MSCI). MSCI is conserved in therian mammals and is essential for normal male fertility. Transcriptomics approaches have demonstrated that in mice, mos...

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Detalles Bibliográficos
Autores principales: Royo, Hélène, Seitz, Hervé, ElInati, Elias, Peters, Antoine H. F. M., Stadler, Michael B., Turner, James M. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624941/
https://www.ncbi.nlm.nih.gov/pubmed/26509798
http://dx.doi.org/10.1371/journal.pgen.1005461