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Epigenetics and Preeclampsia: Defining Functional Epimutations in the Preeclamptic Placenta Related to the TGF-β Pathway

Preeclampsia is a potentially fatal pregnancy disorder affecting millions of women around the globe. Dysregulation in gene and protein expression within key biological pathways controlling angiogenesis has been implicated in the development of preeclampsia. Altered CpG methylation, a type of epimuta...

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Detalles Bibliográficos
Autores principales: Martin, Elizabeth, Ray, Paul D., Smeester, Lisa, Grace, Matthew R., Boggess, Kim, Fry, Rebecca C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624949/
https://www.ncbi.nlm.nih.gov/pubmed/26510177
http://dx.doi.org/10.1371/journal.pone.0141294