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Epigenetics and Preeclampsia: Defining Functional Epimutations in the Preeclamptic Placenta Related to the TGF-β Pathway
Preeclampsia is a potentially fatal pregnancy disorder affecting millions of women around the globe. Dysregulation in gene and protein expression within key biological pathways controlling angiogenesis has been implicated in the development of preeclampsia. Altered CpG methylation, a type of epimuta...
Autores principales: | Martin, Elizabeth, Ray, Paul D., Smeester, Lisa, Grace, Matthew R., Boggess, Kim, Fry, Rebecca C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624949/ https://www.ncbi.nlm.nih.gov/pubmed/26510177 http://dx.doi.org/10.1371/journal.pone.0141294 |
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