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Therapeutic Effects of α1-Antitrypsin on Psedumonas aeruginosa Infection in ENaC Transgenic Mice

Cystic fibrosis (CF) is a genetic disease with many airway pathological features, including aberrant epithelial sodium channel (ENaC) function, persistent Pseudomonas aeruginosa (PA) infection and neutrophil-dominant inflammation. PA infection in CF airways is difficult to treat due to antibiotic re...

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Detalles Bibliográficos
Autores principales: Nichols, David P., Jiang, Di, Happoldt, Carrie, Berman, Reena, Chu, Hong Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624966/
https://www.ncbi.nlm.nih.gov/pubmed/26509529
http://dx.doi.org/10.1371/journal.pone.0141232