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Unc93b Induces Apoptotic Cell Death and Is Cleaved by Host and Enteroviral Proteases

Unc93b is an endoplasmic reticulum (ER)-resident transmembrane protein that serves to bind and traffic toll-like receptors (TLRs) from the ER to their appropriate subcellular locations for ligand sensing. Because of its role in TLR trafficking, Unc93b is necessary for an effective innate immune resp...

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Detalles Bibliográficos
Autores principales: Harris, Katharine G., Coyne, Carolyn B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624986/
https://www.ncbi.nlm.nih.gov/pubmed/26509685
http://dx.doi.org/10.1371/journal.pone.0141383