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Unc93b Induces Apoptotic Cell Death and Is Cleaved by Host and Enteroviral Proteases
Unc93b is an endoplasmic reticulum (ER)-resident transmembrane protein that serves to bind and traffic toll-like receptors (TLRs) from the ER to their appropriate subcellular locations for ligand sensing. Because of its role in TLR trafficking, Unc93b is necessary for an effective innate immune resp...
Autores principales: | Harris, Katharine G., Coyne, Carolyn B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624986/ https://www.ncbi.nlm.nih.gov/pubmed/26509685 http://dx.doi.org/10.1371/journal.pone.0141383 |
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