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Reciprocal regulation of TGF-β and reactive oxygen species: A perverse cycle for fibrosis
Transforming growth factor beta (TGF-β) is the most potent pro-fibrogenic cytokine and its expression is increased in almost all of fibrotic diseases. Although signaling through Smad pathway is believed to play a central role in TGF-β's fibrogenesis, emerging evidence indicates that reactive ox...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625010/ https://www.ncbi.nlm.nih.gov/pubmed/26496488 http://dx.doi.org/10.1016/j.redox.2015.09.009 |