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CLL Exosomes Modulate the Transcriptome and Behaviour of Recipient Stromal Cells and Are Selectively Enriched in miR-202-3p

Bi-directional communication with the microenvironment is essential for homing and survival of cancer cells with implications for disease biology and behaviour. In chronic lymphocytic leukemia (CLL), the role of the microenvironment on malignant cell behaviour is well described. However, how CLL cel...

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Detalles Bibliográficos
Autores principales: Farahani, Mosavar, Rubbi, Carlos, Liu, Luning, Slupsky, Joseph R., Kalakonda, Nagesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625016/
https://www.ncbi.nlm.nih.gov/pubmed/26509439
http://dx.doi.org/10.1371/journal.pone.0141429