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Effects of Methylation Status of CpG Sites within the HPV16 Long Control Region on HPV16-Positive Head and Neck Cancer Cells

OBJECTIVE: To map comprehensively the methylation status of the CpG sites within the HPV16 long control region (LCR) in HPV-positive cancer cells, and to explore further the effects of methylation status of HPV16 LCR on cell bioactivity and E6 and E7 expression. In addition, to analyze the methylati...

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Detalles Bibliográficos
Autores principales: Zhang, Chunlin, Deng, Zeyi, Pan, Xiaoli, Uehara, Takayuki, Suzuki, Mikio, Xie, Minqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625038/
https://www.ncbi.nlm.nih.gov/pubmed/26509736
http://dx.doi.org/10.1371/journal.pone.0141245