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Ursodeoxycholic Acid (UDCA) Exerts Anti-Atherogenic Effects by Inhibiting Endoplasmic Reticulum (ER) Stress Induced by Disturbed Flow

Disturbed blood flow with low-oscillatory shear stress (OSS) is a predominant atherogenic factor leading to dysfunctional endothelial cells (ECs). Recently, it was found that disturbed flow can directly induce endoplasmic reticulum (ER) stress in ECs, thereby playing a critical role in the developme...

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Detalles Bibliográficos
Autores principales: Chung, Jihwa, Kim, Kyoung Hwa, Lee, Seok Cheol, An, Shung Hyun, Kwon, Kihwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625066/
https://www.ncbi.nlm.nih.gov/pubmed/26442866
http://dx.doi.org/10.14348/molcells.2015.0094