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NRROS Negatively Regulates Osteoclast Differentiation by Inhibiting RANKL-Mediated NF-κB and Reactive Oxygen Species Pathways

Negative regulator of reactive oxygen species (NRROS) is known to repress ROS generation in phagocytes. In this study, we examined the roles of NRROS in both osteoclasts and osteoblasts. Our results demonstrate that NRROS negatively regulates the differentiation of osteoclasts, but not osteoblasts....

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Detalles Bibliográficos
Autores principales: Kim, Jung Ha, Kim, Kabsun, Kim, Inyoung, Seong, Semun, Kim, Nacksung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625072/
https://www.ncbi.nlm.nih.gov/pubmed/26442864
http://dx.doi.org/10.14348/molcells.2015.0177