Dynamic Enhancer Methylation - A Previously Unrecognized Switch for Tissue-Type Plasminogen Activator Expression

Tissue-type plasminogen activator (t-PA), which is synthesized in the endothelial cells lining the blood vessel walls, is a key player in the fibrinolytic system protecting the circulation against occluding thrombus formation. Although classical gene regulation has been quite extensively studied in...

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Detalles Bibliográficos
Autores principales: Magnusson, Mia, Lu, Emma Xuchun, Larsson, Pia, Ulfhammer, Erik, Bergh, Niklas, Carén, Helena, Jern, Sverker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625093/
https://www.ncbi.nlm.nih.gov/pubmed/26509603
http://dx.doi.org/10.1371/journal.pone.0141805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625093/
https://www.ncbi.nlm.nih.gov/pubmed/26509603
http://dx.doi.org/10.1371/journal.pone.0141805

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