NMR characterization of HIV-1 reverse transcriptase binding to various non-nucleoside reverse transcriptase inhibitors with different activities

Human immunodeficiency virus type 1 reverse transcriptase (HIV-1 RT) is an important target for antiviral therapy against acquired immunodeficiency syndrome. However, the efficiency of available drugs is impaired most typically by drug-resistance mutations in this enzyme. In this study, we applied a...

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Detalles Bibliográficos
Autores principales: Thammaporn, Ratsupa, Yagi-Utsumi, Maho, Yamaguchi, Takumi, Boonsri, Pornthip, Saparpakorn, Patchreenart, Choowongkomon, Kiattawee, Techasakul, Supanna, Kato, Koichi, Hannongbua, Supa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625163/
https://www.ncbi.nlm.nih.gov/pubmed/26510386
http://dx.doi.org/10.1038/srep15806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625163/
https://www.ncbi.nlm.nih.gov/pubmed/26510386
http://dx.doi.org/10.1038/srep15806

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