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Chemosensory signalling pathways involved in sensing of amino acids by the ghrelin cell

Taste receptors on enteroendocrine cells sense nutrients and transmit signals that control gut hormone release. This study aimed to investigate the amino acid (AA) sensing mechanisms of the ghrelin cell in a gastric ghrelinoma cell line, tissue segments and mice. Peptone and specific classes of amin...

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Detalles Bibliográficos
Autores principales: Vancleef, L., Van Den Broeck, T., Thijs, T., Steensels, S., Briand, L., Tack, J., Depoortere, I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625164/
https://www.ncbi.nlm.nih.gov/pubmed/26510380
http://dx.doi.org/10.1038/srep15725