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Phenotypic variance explained by local ancestry in admixed African Americans

We surveyed 26 quantitative traits and disease outcomes to understand the proportion of phenotypic variance explained by local ancestry in admixed African Americans. After inferring local ancestry as the number of African-ancestry chromosomes at hundreds of thousands of genotyped loci across all aut...

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Detalles Bibliográficos
Autores principales: Shriner, Daniel, Bentley, Amy R., Doumatey, Ayo P., Chen, Guanjie, Zhou, Jie, Adeyemo, Adebowale, Rotimi, Charles N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625172/
https://www.ncbi.nlm.nih.gov/pubmed/26579196
http://dx.doi.org/10.3389/fgene.2015.00324