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Deciphering the association between gene function and spatial gene-gene interactions in 3D human genome conformation

BACKGROUND: A number of factors have been investigated in the context of gene function prediction and analysis, such as sequence identity, gene expressions, and gene co-evolution. However, three-dimensional (3D) conformation of the genome has not been tapped to analyse gene function, probably largel...

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Detalles Bibliográficos
Autores principales: Cao, Renzhi, Cheng, Jianlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625479/
https://www.ncbi.nlm.nih.gov/pubmed/26511362
http://dx.doi.org/10.1186/s12864-015-2093-0