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Oxygen-glucose deprivation regulates BACE1 expression through induction of autophagy in Neuro-2a/APP695 cells

Our previous findings have demonstrated that autophagy regulation can alleviate the decline of learning and memory by eliminating deposition of extracellular beta-amyloid peptide (Aβ) in the brain after stroke, but the exact mechanism is unclear. It is presumed that the regulation of beta-site APP-c...

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Detalles Bibliográficos
Autores principales: Chen, Rong-fu, Zhang, Ting, Sun, Yin-yi, Sun, Ya-meng, Chen, Wen-qi, Shi, Nan, Shen, Fang, Zhang, Yan, Liu, Kang-yong, Sun, Xiao-jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625509/
https://www.ncbi.nlm.nih.gov/pubmed/26604904
http://dx.doi.org/10.4103/1673-5374.165511