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The activation of pyrin domain-containing-3 inflammasome depends on lipopolysaccharide from Porphyromonas gingivalis and extracellular adenosine triphosphate in cultured oral epithelial cells

BACKGROUND: Gingival epithelial cells are the major population of the gingival tissue, acting as the front-line defense against microbial intrusion and regulating the homeostasis of the periodontal tissue in health and disease via NLR family pyrin domain-containing-3 (NLRP3) inflammasome, which reco...

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Detalles Bibliográficos
Autores principales: Guo, Wei, Wang, Peng, Liu, Zhonghao, Yang, Pishan, Ye, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625523/
https://www.ncbi.nlm.nih.gov/pubmed/26511096
http://dx.doi.org/10.1186/s12903-015-0115-6