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Multifunctional roles of leader protein of foot-and-mouth disease viruses in suppressing host antiviral responses

Foot-and-mouth disease virus (FMDV) leader protein (L(pro)) is a papain-like proteinase, which plays an important role in FMDV pathogenesis. L(pro) exists as two forms, Lab and Lb, due to translation being initiated from two different start codons separated by 84 nucleotides. L(pro) self-cleaves fro...

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Detalles Bibliográficos
Autores principales: Liu, Yingqi, Zhu, Zixiang, Zhang, Miaotao, Zheng, Haixue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625562/
https://www.ncbi.nlm.nih.gov/pubmed/26511922
http://dx.doi.org/10.1186/s13567-015-0273-1