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Multifunctional roles of leader protein of foot-and-mouth disease viruses in suppressing host antiviral responses
Foot-and-mouth disease virus (FMDV) leader protein (L(pro)) is a papain-like proteinase, which plays an important role in FMDV pathogenesis. L(pro) exists as two forms, Lab and Lb, due to translation being initiated from two different start codons separated by 84 nucleotides. L(pro) self-cleaves fro...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625562/ https://www.ncbi.nlm.nih.gov/pubmed/26511922 http://dx.doi.org/10.1186/s13567-015-0273-1 |