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Cancer anti-angiogenesis vaccines: Is the tumor vasculature antigenically unique?

Angiogenesis is essential for the growth and metastasis of solid tumors. The tumor endothelium exists in a state of chronic activation and proliferation, fueled by the tumor milieu where angiogenic mediators are aberrantly over-expressed. Uncontrolled tumor growth, immune evasion, and therapeutic re...

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Detalles Bibliográficos
Autores principales: Wagner, Samuel C., Ichim, Thomas E., Ma, Hong, Szymanski, Julia, Perez, Jesus A., Lopez, Javier, Bogin, Vladimir, Patel, Amit N., Marincola, Francisco M., Kesari, Santosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625691/
https://www.ncbi.nlm.nih.gov/pubmed/26510973
http://dx.doi.org/10.1186/s12967-015-0688-5