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Is Whole Exome Sequencing Clinically Practical in the Management of Pediatric Crohn’s Disease?

BACKGROUND/AIMS: The aim of this study was to identify the profile of rare variants associated with Crohn’s disease (CD) using whole exome sequencing (WES) analysis of Korean children with CD and to evaluate whether genetic profiles could provide information during medical decision making. METHODS:...

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Detalles Bibliográficos
Autores principales: Oh, Seak Hee, Baek, Jiwon, Kim, Kyung Mo, Lee, Eun-Ju, Jung, Yusun, Lee, Yeoun Joo, Jin, Hyun-Seung, Ye, Byong Duk, Yang, Suk-Kyun, Lee, Jong-Keuk, Seo, Eul-Ju, Lim, Hyun Taek, Lee, Inchul, Song, Kyuyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Office of Gut and Liver 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625707/
https://www.ncbi.nlm.nih.gov/pubmed/26503572
http://dx.doi.org/10.5009/gnl15176