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Fluorescent protein-tagged Vpr dissociates from HIV-1 core after viral fusion and rapidly enters the cell nucleus

BACKGROUND: HIV-1 Vpr is recruited into virions during assembly and appears to remain associated with the viral core after the reverse transcription and uncoating steps of entry. This feature has prompted the use of fluorescently labeled Vpr to visualize viral particles and to follow trafficking of...

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Detalles Bibliográficos
Autores principales: Desai, Tanay M., Marin, Mariana, Sood, Chetan, Shi, Jiong, Nawaz, Fatima, Aiken, Christopher, Melikyan, Gregory B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625717/
https://www.ncbi.nlm.nih.gov/pubmed/26511606
http://dx.doi.org/10.1186/s12977-015-0215-z