Cargando…

Fluorescent protein-tagged Vpr dissociates from HIV-1 core after viral fusion and rapidly enters the cell nucleus

BACKGROUND: HIV-1 Vpr is recruited into virions during assembly and appears to remain associated with the viral core after the reverse transcription and uncoating steps of entry. This feature has prompted the use of fluorescently labeled Vpr to visualize viral particles and to follow trafficking of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Desai, Tanay M., Marin, Mariana, Sood, Chetan, Shi, Jiong, Nawaz, Fatima, Aiken, Christopher, Melikyan, Gregory B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625717/ https://www.ncbi.nlm.nih.gov/pubmed/26511606 http://dx.doi.org/10.1186/s12977-015-0215-z

Ejemplares similares

Direct Vpr-Vpr Interaction in Cells monitored by two Photon Fluorescence Correlation Spectroscopy and Fluorescence Lifetime Imaging
por: Fritz, Joëlle V, et al.
Publicado: (2008)

Visualization of Content Release from Cell Surface-Attached Single HIV-1 Particles Carrying an Extra-Viral Fluorescent pH-Sensor
por: Sood, Chetan, et al.
Publicado: (2016)

HIV-1 Vpr N-terminal tagging affects alternative splicing of the viral genome
por: Baeyens, Ann, et al.
Publicado: (2016)

Vpr makes holes
por: Wells, William A.
Publicado: (2001)

Vpr Is a VIP: HIV Vpr and Infected Macrophages Promote Viral Pathogenesis
por: Lubow, Jay, et al.
Publicado: (2020)

Localization and functions of native and eGFP-tagged capsid proteins in HIV-1 particles
por: Francis, Ashwanth C., et al.
Publicado: (2022)

Dissociable roles of the nucleus accumbens core and shell subregions in the expression and extinction of conditioned fear
por: Dutta, Sohini, et al.
Publicado: (2021)

IFITM3 Restricts Influenza A Virus Entry by Blocking the Formation of Fusion Pores following Virus-Endosome Hemifusion
por: Desai, Tanay M., et al.
Publicado: (2014)

Vpr loosens chromatid ties
por: Short, Ben
Publicado: (2011)

Localization of HIV-1 Vpr to the nuclear envelope: Impact on Vpr functions and virus replication in macrophages
por: Jacquot, Guillaume, et al.
Publicado: (2007)

Effect on HIV-1 Gene Expression, Tat-Vpr Interaction and Cell Apoptosis by Natural Variants of HIV-1 Tat Exon 1 and Vpr from Northern India
por: Lata, Sneh, et al.
Publicado: (2013)

Dissociable Roles of Dopamine Within the Core and Medial Shell of the Nucleus Accumbens in Memory for Objects and Place
por: Nelson, Andrew J. D., et al.
Publicado: (2010)

Characterization of natural HIV-1 Tat and Vpr variants from Northern India
por: Lata, Sneh, et al.
Publicado: (2012)

Time-Resolved Imaging of Single HIV-1 Uncoating In Vitro and in Living Cells
por: Francis, Ashwanth C., et al.
Publicado: (2016)

The Vibrio cholerae VprA-VprB Two-Component System Controls Virulence through Endotoxin Modification
por: Herrera, Carmen M., et al.
Publicado: (2014)

Visible Multiphoton Dissociation of Chromophore-Tagged Peptides
por: Bouakil, Mathilde, et al.
Publicado: (2017)

Cyclosporines Antagonize the Antiviral Activity of IFITMProteins by Redistributing Them toward the Golgi Apparatus
por: Prikryl, David, et al.
Publicado: (2023)

Centrosome amplification and aneuploidy driven by the HIV-1-induced Vpr•VprBP•Plk4 complex in CD4(+) T cells
por: Park, Jung-Eun, et al.
Publicado: (2023)

Cloning of a Novel vpr Gene Encoding a Minor Fibrinolytic Enzyme from Bacillus subtilis SJ4 and the Properties of Vpr
por: Yao, Zhuang, et al.
Publicado: (2020)

A bright and photostable photoconvertible fluorescent protein for fusion tags
por: McKinney, Sean A., et al.
Publicado: (2009)

Involvement of Lgl and Mahjong/VprBP in Cell Competition
por: Tamori, Yoichiro, et al.
Publicado: (2010)

HIV-1 Vpr—a still “enigmatic multitasker”
por: Guenzel, Carolin A., et al.
Publicado: (2014)

Visualizing Vpr-Induced G2 Arrest and Apoptosis
por: Murakami, Tomoyuki, et al.
Publicado: (2014)

Illuminating the Role of Vpr in HIV Infection of Myeloid Cells
por: Nodder, Sarah Beth, et al.
Publicado: (2019)

Interferon-induced transmembrane protein 3 blocks fusion of sensitive but not resistant viruses by partitioning into virus-carrying endosomes
por: Suddala, Krishna C., et al.
Publicado: (2019)

Characterization of the Molecular Determinants of Primary HIV-1 Vpr Proteins: Impact of the Q65R and R77Q Substitutions on Vpr Functions
por: Jacquot, Guillaume, et al.
Publicado: (2009)

Correction for Herrera et al., The Vibrio cholerae VprA-VprB Two-Component System Controls Virulence through Endotoxin Modification
por: Herrera, Carmen M., et al.
Publicado: (2015)

Genetically encoded fluorescent tags
por: Thorn, Kurt
Publicado: (2017)

HIV-1 Vpr Induces the Degradation of ZIP and sZIP, Adaptors of the NuRD Chromatin Remodeling Complex, by Hijacking DCAF1/VprBP
por: Maudet, Claire, et al.
Publicado: (2013)

Molecule of the month: HIV-1 protein Vpr and miRNA
por: Shapshak, Paul
Publicado: (2012)

Naturally occurring Vpr inhibitors from medicinal plants of Myanmar
por: Win, Nwet Nwet, et al.
Publicado: (2017)

New Insights Into the Virus-to-Prokaryote Ratio (VPR) in Marine Sediments
por: Wei, Miao, et al.
Publicado: (2020)

Vpr and Its Cellular Interaction Partners: R We There Yet?
por: Fabryova, Helena, et al.
Publicado: (2019)

Mannose receptor is an HIV restriction factor counteracted by Vpr in macrophages
por: Lubow, Jay, et al.
Publicado: (2020)

PP2A(1) Binding, Cell Transducing and Apoptotic Properties of Vpr(77–92): A New Functional Domain of HIV-1 Vpr Proteins
por: Godet, Angélique N., et al.
Publicado: (2010)

Synchronized Retrovirus Fusion in Cells Expressing Alternative Receptor Isoforms Releases the Viral Core into Distinct Sub-cellular Compartments
por: Padilla-Parra, Sergi, et al.
Publicado: (2012)

Cytotoxic T lymphocyte effector function is independent of nucleus–centrosome dissociation
por: Lui-Roberts, Winnie W Y, et al.
Publicado: (2012)

An Endogenously Tagged Fluorescent Fusion Protein Library in Mouse Embryonic Stem Cells
por: Harikumar, Arigela, et al.
Publicado: (2017)

Characterization of HIV-1 Vpr Nuclear Import: Analysis of Signals and Pathways
por: Jenkins, Yonchu, et al.
Publicado: (1998)

Regulation of the HIV-1 promoter by HIF-1α and Vpr proteins
por: Deshmane, Satish L, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_vdtchm6sfb9jg59fa3bvhfjnii