Impact of naturally occurring amino acid variations on the detection of HIV-1 p24 in diagnostic antigen tests

BACKGROUND: The detection of HIV-1 p24 antigen in diagnostic tests relies on antibodies binding to conserved areas of the protein to cover the full range of HIV-1 subtypes. Using a panel of 43 different virus-like particles (VLPs) expressing Gag from clinical HIV-1 isolates, we previously found that...

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Detalles Bibliográficos
Autores principales: Vetter, Beatrice N., Orlowski, Vanessa, Niederhauser, Christoph, Walter, Louise, Schüpbach, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625719/
https://www.ncbi.nlm.nih.gov/pubmed/26511217
http://dx.doi.org/10.1186/s12879-015-1174-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625719/
https://www.ncbi.nlm.nih.gov/pubmed/26511217
http://dx.doi.org/10.1186/s12879-015-1174-7

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