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Impact of naturally occurring amino acid variations on the detection of HIV-1 p24 in diagnostic antigen tests
BACKGROUND: The detection of HIV-1 p24 antigen in diagnostic tests relies on antibodies binding to conserved areas of the protein to cover the full range of HIV-1 subtypes. Using a panel of 43 different virus-like particles (VLPs) expressing Gag from clinical HIV-1 isolates, we previously found that...
Autores principales: | Vetter, Beatrice N., Orlowski, Vanessa, Niederhauser, Christoph, Walter, Louise, Schüpbach, Jörg |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625719/ https://www.ncbi.nlm.nih.gov/pubmed/26511217 http://dx.doi.org/10.1186/s12879-015-1174-7 |
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