B cell epitopes on infliximab identified by oligopeptide microarray with unprocessed patient sera

BACKGROUND: Autoimmune diseases like rheumatoid arthritis and inflammatory bowel disease are treated with TNF-alpha-blocking antibodies such as infliximab and adalimumab. A common side effect of therapeutic antibodies is the induction of anti-drug antibodies, which may reduce therapeutic efficacy. M...

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Detalles Bibliográficos
Autores principales: Homann, Arne, Röckendorf, Niels, Kromminga, Arno, Frey, Andreas, Jappe, Uta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625721/
https://www.ncbi.nlm.nih.gov/pubmed/26511203
http://dx.doi.org/10.1186/s12967-015-0706-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4625721/
https://www.ncbi.nlm.nih.gov/pubmed/26511203
http://dx.doi.org/10.1186/s12967-015-0706-7

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